As of 9:15 a.m., the 225-issue Nikkei Stock Average fell 48.85 points, or 0.25 percent, from Tuesday to 19,589.96.
The broader Topix index of all First Section issues on the Tokyo Stock Exchange, meanwhile, lost 2.36 points, or 0.16 percent, at 1,431.15.
Mining and marine transportation, and iron and steel issues comprised those that gained the most in the opening minutes after the morning bell.
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