The 225-issue Nikkei Stock Average dropped 123.33 points, or 0.55 percent, from Thursday to close the day at 22,478.79.
The broader Topix index of all First Section issues on the Tokyo Stock Exchange, meanwhile, lost 0.29 point, or 0.02 percent, to finish at 1,582.80.
Air transportation and securities house issues led notable gainers, while iron and steel, and nonferrous metal issues comprised those that declined the most by the close of play.
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