The route, operated by China's low-cost carrier Spring Airlines using an Airbus A320 aircraft, is the first direct flight linking the cities.
Scheduled every day, the outbound flight leaves Shenzhen Bao'an International Airport at 5:55 a.m. and arrives at Nagoya's Central Japan International Airport at 10:10 a.m. local time.
The return flight departs Nagoya at 10:40 p.m. local time and arrives in Shenzhen, southern China's Guangdong Province, at 2 a.m. the next day.
Last year, over 8 million Chinese tourists visited Japan, up 13.9 percent year on year.
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