Shares of Trip.com Group and JD.com increased 3.37 percent and 1.08 percent, respectively, leading the gainers in the top 10 stocks of the index.
Shares of Yum China Holdings and New Oriental Education & Technology Group declined 1.88 percent and 1.03 percent, respectively, the top two laggards.
U.S. stocks closed mostly higher on Tuesday after U.S. President Donald Trump's speech on the country's economy and stock market.
The Dow Jones Industrial Average was unchanged at close to 27,691.49. The S&P 500 increased 4.83 points, or 0.16 percent, to 3,091.84. The Nasdaq Composite Index increased 21.81 points, or 0.26 percent, to 8,486.09.
Trump on Tuesday criticized Federal Reserve's monetary policies, saying the central bank's hesitation in lowering the interest rates capped gains in U.S. economy and stock market.
He noted that since his election, the S&P 500 has risen more than 45 percent, the Dow Jones Industrial Average has increased over 50 percent and the Nasdaq Composite has been up 60 percent.
"If we had a Federal Reserve that worked with us, you could have added another 25 percent to each of those numbers, I guarantee you that," Trump said.
As of Monday, the S&P U.S. Listed China 50 index stood at 3,059.69, marking a 5.70-percent increase for the month-to-date returns and a 33.53-percent gain for the year-to-date returns.
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