The Shenzhen Component Index closed 2.18 percent higher at 12,370.95 points.
The combined turnover of stocks covered by the two indices came in at 1.08 trillion yuan (170.94 billion U.S. dollars), down from 1.16 trillion yuan on the previous trading day.
Stocks related to COVID-19 testing and treatment and traditional Chinese medicine led the gains. Stocks in sectors such as precious metals and agriculture posted the biggest declines.
The ChiNext Index, tracking China's NASDAQ-style board of growth enterprises, gained 2.67 percent to close at 2,635.19 points.
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