The Dow Jones Industrial Average decreased 117.72 points, or 0.34 percent, to 34,378.34. The S&P 500 was down 10.54 points, or 0.24 percent, to 4,350.65. The Nasdaq Composite Index fell 20.28 points, or 0.14 percent, to 14,465.92.
Six of the 11 primary S&P 500 sectors ended in red, with communication services and technology down 1.05 percent and 0.51 percent, respectively, leading the laggards. Real estate rose 1.34 percent, the best-performing group.
U.S.-listed Chinese companies traded mostly lower with eight of the top 10 stocks by weight in the S&P U.S. Listed China 50 index ending the day on a downbeat note.
Wall Street will look to economic highlights, including U.S. Consumer Price Index data on Wednesday and retail sales data on Friday.
Investors are also awaiting earnings reports, with plenty of big-name banks and financial companies on deck to report this week.
On Monday, U.S. stocks closed lower with the Dow down 250 points.
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