The 225-issue Nikkei Stock Average lost 74.56 points, or 0.35 percent, from Tuesday to close the day at 21,129.72. The broader Topix index of all First Section issues on the Tokyo Stock Exchange, meanwhile, dropped 7.10 points, or 0.45 percent, to finish at 1,554.22.
Miscellaneous product, real estate and oil and coal product-linked issues comprised those that declined the most by the close of play.
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