The 225-issue Nikkei Stock Average gained 49.21 points, or 0.22 percent, from Thursday to close the day at 22,799.81.
The broader Topix index of all First Section issues on the Tokyo Stock Exchange, meanwhile, gained 4.70 points, or 0.29 percent, to close at 1,648.44.
Pharmaceutical, chip and precision instrument-related issues comprised those that gained the most by the close of play.
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