As of 9:15 a.m., the 225-issue Nikkei Stock Average dropped 311.76 points, or 1.46 percent, from Thursday to 21,017.36.
The broader Topix index of all First Section issues on the Tokyo Stock Exchange, meanwhile, lost 25.25 points, or 1.67 percent, to 1,490.46.
Mining, iron and steel, and securities house-linked issues comprised those that declined the most in the opening minutes after the morning bell.
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