The Dow Jones Industrial Average fell 150.57 points, or 0.44 percent, to 34,283.27. The S&P 500 rose 9.91 points, or 0.23 percent, to 4,290.61. The Nasdaq Composite Index jumped 140.12 points, or 0.98 percent, to 14,500.51.
Seven of the 11 primary S&P 500 sectors ended in green, with technology up 1.11 percent, leading the gainers. Energy tumbled 3.33 percent, the worst-performing group.
U.S.-listed Chinese companies traded mostly higher with six of the top 10 stocks by weight in the S&P U.S. Listed China 50 index ending the day on an upbeat note.
Investors awaited a slew of key economic data as U.S. Manufacturing Purchasing Managers' Index is slated for Thursday and the highly-anticipated June payrolls report is expected on Friday.
For last week, the Dow surged 3.4 percent, the S&P 500 rallied 2.7 percent and the tech-heavy Nasdaq Composite advanced 2.4 percent, as investors parsed readings on inflation and reassessed the shape of the economy.
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