The Dow Jones Industrial Average fell 208.98 points, or 0.60 percent, to 34,577.37. The S&P 500 lost 8.80 points, or 0.20 percent, to 4,343.54. The Nasdaq Composite Index increased 24.32 points, or 0.17 percent, to 14,663.64.
Seven of the 11 primary S&P 500 sectors ended in red, with energy down 3.2 percent, leading the laggards. Real estate rose 0.85 percent, the best-performing group.
U.S.-listed Chinese companies traded mostly lower with nine of the top 10 stocks by weight in the S&P U.S. Listed China 50 index ending the day on a downbeat note.
On the economic front, U.S. Services PMI (Purchasing Managers' Index) slipped to 60.1 percent in June from the May's reading of 64 percent, the Institute for Supply Management reported on Tuesday. Economists surveyed by Dow Jones and The Wall Street Journal had forecast the index would total 63.3 percent in June. A reading above 50 percent indicates expansion in the service sector while a reading below 50 percent signals contraction.
Investors will also look to minutes from the Federal Reserve's last policy meeting slated for Wednesday and the nation's weekly jobless claims numbers to be released by the Department of Labor on Thursday.
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