The Dow Jones Industrial Average decreased 106.66 points, or 0.30 percent, to 35,101.85. The S&P 500 fell 4.17 points, or 0.09 percent, to 4,432.35. The Nasdaq Composite Index increased 24.42 points, or 0.16 percent, to 14,860.18.
Seven of the 11 primary S&P 500 sectors ended in red, with energy down 1.48 percent, leading the laggards. The health care group rose 0.38 percent, outpacing the rest.
U.S.-listed Chinese companies traded mostly higher with seven of the top 10 stocks by weight in the S&P U.S. Listed China 50 index ending the day on an upbeat note.
Investors eyed surging COVID-19 cases as the pandemic continues in the United States, with the Delta variant in a sustained uptrend and hospitalizations on the rise.
The average daily increase of cases in the United States was over 97,000 in the seven-day period ending Sunday, compared with a seven-day average of around 17,800 daily cases a month ago, according to the latest data compiled by the U.S. Centers for Disease Control and Prevention.
On the economic front, U.S. Labor Department reported on Monday that U.S. job openings hit a record 10.1 million in June.
For the week ending Aug. 6, the Dow rose 0.8 percent, while the S&P 500 and the tech-heavy Nasdaq climbed 0.9 percent and 1.1 percent, respectively.
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