The Dow Jones Industrial Average decreased 211.17 points, or 0.58 percent, to 35,931.05. The S&P 500 dipped 12.23 points, or 0.26 percent, to 4,688.67. The Nasdaq Composite Index slid 52.28 points, or 0.33 percent, to 15,921.57.
Seven of the 11 primary S&P 500 sectors ended in red, with energy and financials down 1.74 percent and 1.11 percent, leading the laggards. Real estate rose 0.64 percent, the best-performing group.
U.S.-listed Chinese companies traded mostly lower with nine of the top 10 stocks by weight in the S&P U.S. Listed China 50 index ending the day on a downbeat note.
On Tuesday, U.S. equities advanced with the tech-heavy Nasdaq closing up 120 points, bolstered by better-than-expected economic data.
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