As of 9:15 a.m., the 225-issue Nikkei Stock Average dropped 129.27 points, or 0.58 percent, from Wednesday to 22,326.49.
The broader Topix index of all First Section issues on the Tokyo Stock Exchange, meanwhile, lost 8.06 points, or 0.51 percent, at 1,579.03.
Air transportation, mining, and iron and steel-linked issues comprised those that declined the most in the opening minutes after the morning bell.
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