As of 9:15 a.m., the 225-issue Nikkei Stock Average lost 37.19 points, or 0.14 percent, from Tuesday to 27,121.44.
The broader Topix index of all First Section issues on the Tokyo Stock Exchange, meanwhile, added 6.21 points, or 0.35 percent, at 1,797.43.
Food and glass and ceramic product issues led notable decliners, while mining and marine transportation issues comprised those that gained the most in the opening minutes after the morning bell.
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