The 225-issue Nikkei Stock Average lost 100.30 points, or 0.45 percent, from Wednesday to close the day at 22,355.46.
The broader Topix index of all First Section issues on the Tokyo Stock Exchange, meanwhile, lost 4.00 points, or 0.25 percent, to finish at 1,583.09.
Air transportation, mining, and oil and coal product-linked issues comprised those that declined the most by the close of play.
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