The 225-issue Nikkei Stock Average dropped 260.10 points, or 1.11 percent, from Thursday to close the day at 23,205.43.
The broader Topix index of all First Section issues on the Tokyo Stock Exchange, meanwhile, fell 14.64 points, or 0.90 percent, to finish at 1,616.60.
Precision instrument, information and communication, and pharmaceutical issues comprised those that declined the most by the close of play.
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