As of 9:15 a.m., the 225-issue Nikkei Stock Average dropped 338.36 points, or 1.17 percent, from Tuesday to 28,657.56.
The broader Topix index of all First Section issues on the Tokyo Stock Exchange, meanwhile, lost 23.00 points, or 1.17 percent, at 1,948.48.
Air transportation, mining and marine transportation issues comprised those that declined the most in the opening minutes after the morning bell.
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