The 225-issue Nikkei Stock Average lost 241.59 points, or 1.04 percent, from Tuesday to close the day at 23,032.54.
The broader Topix index of all First Section issues on the Tokyo Stock Exchange, meanwhile, fell 15.49 points, or 0.96 percent, to finish at 1,605.40.
Mining, bank and real estate-linked issues comprised those that declined the most by the close of play.
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