The 225-issue Nikkei Stock Average gained 42.23 points, or 0.18 percent, from Friday to 23,858.86.
The broader Topix index of all First Section issues on the Tokyo Stock Exchange, meanwhile, shed 1.96 points, or 0.11 percent, at 1,731.11.
Pharmaceutical, service and precision instrument-linked issues comprised those that gained the most by the morning break.
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